Bioinformatics and Microbial Biotechnology Laboratory (BMBL)
Location: Room: 639A, 6th Floor, Jatiya Kabi Kazi Nazrul Islam Academic Building, JUST
Research outline
The research activities of the BMBL laboratory are centered around molecular biology, microbial genomics, computational biology, and bioinformatics. Our current research focus on:
- Genome sequencing and annotation of diverse microbial isolates from environmental and clinical origins, contributing to the understanding of bacterial diversity, pathogenicity, and beneficial traits.
- Comparative genomics and pan-genome analysis to uncover genetic variation, biosynthetic gene clusters, and antimicrobial resistance determinants in bacteria such as Lacticaseibacillus paracasei and Corynebacterium glutamicum.
- Green synthesis and biomedical evaluation of nanoparticles, such as ZnO and Au nanoparticles, with potential antimicrobial and anticancer applications.
Skills and background we are looking for in prospective students
The BMBL laboratory welcomes curious and dedicated students at all levels (undergraduate, postgraduate and PhD) who are passionate about molecular biology, microbiology, and computational life sciences. General attributes we value (all levels):
- Intellectual curiosity and a willingness to learn.
- Careful and ethical research practice.
- Teamwork, clear communication, and a proactive attitude.
- Commitment to producing high-quality, reproducible work.
What you can expect to learn in this laboratory?
- Combines molecular experimentation with computational analysis.
- Molecular characterization of microbial systems.
- Use of computational tools for comparative genomics, pan-genome analysis, and virtual drug screening.
- Skills in experimental design, critical analysis, and translating results into impactful outputs.
Key publications
- Rahi, Md. Sifat, Rahman, Md. Shahedur et. al., Unveiling the Therapeutic Potential of Piper chaba Hunter: Computational Approaches Shed Light on Targeting Proteins in Alzheimer’s Disease, BioMed Research International, 2025, 8892801, pages, 2025. https://doi.org/10.1155/bmri/8892801
- Rahman MS, Antor A, Sojol MH, Hossen MM, Hasan M, Sarker RH, Jamal MAHM.2025. Draft genome assembly of Lacticaseibacillus paracasei MSR2 isolated from Bangladesh. Microbiol Resour Announc14:e01314-24. https://doi.org/10.1128/mra.01314-24
- Rahman MS, Shimul MEK, Parvez MAK (2024) Comprehensive analysis of genomic variation, pan-genome and biosynthetic potential of Corynebacterium glutamicum strains. PLOS ONE 19(5): e0299588. https://doi.org/10.1371/journal.pone.0299588
- Tamanna, T., & Rahman, Md. S. (2023). Leveraging immunoinformatics for developing a multi-epitope subunit vaccine against Helicobacter pylori and Fusobacterium nucleatum. Journal of Biomolecular Structure and Dynamics, 43(3), 1552–1565. https://doi.org/10.1080/07391102.2023.2292295
- Ahmed, F.F., Das, A.D., Sumi, M.J. et al. Identification of genetic biomarkers, drug targets and agents for respiratory diseases utilising integrated bioinformatics approaches. Sci. Rep. 13, 19072 (2023). https://doi.org/10.1038/s41598-023-46455-8
Members and Contacts
Lab head:
Prof. Dr. Md. Shahedur Rahman
Professor, Department of Genetic Engineering and Biotechnology
Email: ms.rahman@just.edu.bd
Associated members:
Ph.D. students:
- Tanjin Tammanna
Undergraduate students:
- Abida Ahsan
- Nafisa Tasnim
- Saba-E-Tabassum
- Jalis Mahmud
